The band opened with 'Quick Escape' on Tuesday (May 3), but before performing, Vedder acknowledged drummer Matt Cameron's friendship with Hawkins.
"[Hawkins] emitted something very incredible and very special," he told the audience.
"We’re all missing him, and so, Matt, I’m sorry again for your loss. But it just gives us another chance to say how much we appreciate you as well."
Watch the moment below.